Acetyl hexapeptide-8 or acetyl hexapeptide-8 amide is a man-made ingredient used in anti-wrinkle cosmetic products. This peptide, a fragment of SNAP-25 and a substrate for botulinum toxin (Botox), is crafted synthetically.
Primarily utilized in skin care formulations, Acetyl hexapeptide-8, formerly recognized as Argireline and also known as acetyl hexapeptide-3, boasts water-binding and skin-rejuvenating properties contributing to a youthful skin appearance.
This peptide aims to diminish the visible signs of aging, particularly the deep lines and wrinkles that emerge around the forehead and eyes. Chemically, when acetyl hexapeptide-8 is applied to specific facial areas, it blocks muscle movements or contractions, such as those seen when smiling or frowning, by inhibiting the necessary reactions.
As a peptide that inhibits neurotransmitter activity, Acetyl hexapeptide-8 operates at the skin’s surface to reduce the appearance of expression lines, though it does not serve as a substitute for professional wrinkle-smoothing treatments done in medical settings. Supplier research indicates that this peptide also supports the skin’s collagen production and helps maintain a firmer skin look.
Acetyl Hexapeptide-8 typically comes in the form of a white, crystalline powder. A variety of skincare products, including serums, creams, and anti-aging treatments, incorporate Acetyl Hexapeptide-8 in their formulations.